As long as you observe power and impedance requirements you can actually use 'stereo' speakers and 'guitar' speakers interchangeably from an electronics point of view.
They will however probably sound horrible when swapped around.
This is a result of frequency response. 'Stereo' speakers are designed for a fairly flat response because the intent is to accurately reproduce the source, whereas 'guitar' speakers are designed to have all kinds of different peaks and toughs in frequency response so they sound "musical" when driven from a guitar amp.
To answer your specific question, I would absolutely try out an old 5" Rola in a low power guitar amp!
Do you have any idea what kind of power rating the speakers have?